Electrochemical behavior of anagrelide and its determination
نویسندگان
چکیده
A simple, accurate and sensitive voltammetric method for determination of Anagrelide (ANG) using β cyclodextrin modified carbon paste electrode (CDMCPE) is developed. CDMCPE exhibited significantly increased sensitivity and selectivity for ANG compared to Carbon paste electrode. Peak currents showed a linear response in the concentration range 1.8 × 10-9 to 1.6 × 10-6 M at CDMCPE. Limit of detection (LOD) and limit of quantization LOQ were found to be 2.2 × 10-8 to 0.733 × 10-7 M with a correlation coefficient of 0.9916. The proposed method has been successfully applied for the determination of ANG in spiked serum sample, urine samples and pharmaceutical formulations.
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